What is the long- term effect?

The long- term effects of Cocaine use, is most obviously addiction. Individuals seek to gain the pleasurable feeling more regularly, but due to the desensitisation of neuronal receptors individuals often fail to achieve as much pleasure. This leads to more frequent use of the substance and increased doses to intensify this euphoric feeling; the individual is addicted. Other long-term effects involve irritability, restlessness, and paranoia. The most horrific consequence of cocaine abuse is death; a user can experience acute cardiovascular arrests, such as a heart attack or stroke, which could result in sudden death. Cocaine-related deaths are often a result of cardiac arrest or seizure followed by respiratory arrest